Bottom-up sample preparation for the LC-MS/MS quantification of anti-cancer monoclonal antibodies in bio matrices

Therapeutic monoclonal antibodies (mAbs) are quickly taking up the remedy of many malignancies, and an astonishing variety of mAbs is in growth. This causes a excessive demand for quantification of mAbs in biomatrices each for measuring therapeutic mAb concentrations and to help pharmacokinetics and pharmacodynamics research. Conventionally, ligand-binding assays are used for these functions, however […]