Solitary extramedullary plasmacytoma of the nasopharynx: The role of flow cytometry

Solitary extramedullary plasmacytoma of the nasopharynx: The role of flow cytometry

Extramedullary plasmacytoma (EMP) represents a definite but uncommon entity among the many plasma cell neoplasms. Given its rarity, no therapeutic consensus has been met. We report the case of a 57-year-old man with a one-year historical past of nasal congestion and occasional dyspnoea. Imaging confirmed a hypermetabolic mass in the proper nasopharynx extending backward in […]

Limitations of VS38c labeling in the detection of plasma cell myeloma by flow cytometry

Limitations of VS38c labeling in the detection of plasma cell myeloma by flow cytometry

Plasma cell myeloma (a number of myeloma [MM]) is a malignant neoplasm originating from the plasma cells. Apart from different strategies, circulation cytometric evaluation of the affected person’s bone marrow aspirate has an vital function within the prognosis and in addition within the response evaluation. Because the cell floor markers, used for figuring out irregular […]

Highly sensitive detection of antibody nonspecific interactions using flow cytometry

The quickly evolving nature of antibody drug improvement has resulted in applied sciences that generate huge numbers (a whole bunch to hundreds) of lead antibody candidates throughout early discovery. These candidates have to be quickly pared all the way down to establish probably the most drug-like candidates for in-depth evaluation of their security and efficacy, […]

Unsupervised flow cytometry analysis in hematological malignancies: A new paradigm

Unsupervised flow cytometry analysis in hematological malignancies: A new paradigm

Ever since hematopoietic cells grew to become “occasions” enumerated and characterised in suspension by cell counters or move cytometers, researchers and engineers have strived to refine the acquisition and show of the digital alerts generated. A big array of options was then developed to establish at finest the quite a few cell subsets that may […]

Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses

Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses

Psychotic issues are widespread and disabling psychological circumstances. The relative significance of immune-related mechanisms in psychotic issues stays topic of debate. Right here, we current a large-scale retrospective research of blood and cerebrospinal fluid (CSF) immune cell profiles of psychosis spectrum sufferers. We carried out primary CSF evaluation and multi-dimensional movement cytometry of CSF and […]

Isolation and immunophenotyping by flow cytometry of canine peripheral blood and intraepithelial and lamina propria duodenal T lymphocytes

Isolation and immunophenotyping by flow cytometry of canine peripheral blood and intraepithelial and lamina propria duodenal T lymphocytes

The intestine related lymphoid tissue (GALT) effector websites play a vital position on the pathogenesis of many immune-mediated gastrointestinal ailments. The lymphocytes at these effector websites are principally T cells which current necessary morphological, phenotypical and purposeful variations. Circulation cytometry (FC) is likely one of the mostly used methods to characterize intestinal lymphocytes in human […]

BioMag Plus Concanavalin A

Cat # 86057-3 Size: 3ml Brand: Polysciences Description Column and bead-based separation methods are highly dependent on the speed and ease of affinity binding systems. Ligands such as streptavidin, antibodies, and lectins are used both to capture specifically labelled targets and for the isolation of cells and biomolecules that naturally express the binding partner of […]

SARS-CoV/SARS-CoV-2 Spike antibody,Chimeric MAb

Product name SARS-CoV / SARS-CoV-2 spike antibody, chimeric MAb Validated applications ELISA , Neutralization Application Notes IHC, FCM, IF, IP et al. the applications have not been validated. (Antibody applications have not been validated with corresponding virus-positive samples. Optimal concentrations/dilutions must be determined by the end-user). Specificity Peak of SARS coronavirus It is cross-reactive in […]

Prigrow III Medium

Specifications¬† Description The ABM PriGrow media series for mammalian cell culture is comprised of high-quality, specific formulations for optimal growth of different types of primary cells. PriGrow media is offered as a basal formula, without serum or antibiotics to give the end-user the flexibility to add more supplements and serums if needed. Each lot has […]

Proteinase K

Description Proteinase K, originally isolated from the fungus Tritirachium album, is a serine protease with broad substrate specificity and relatively high proteolytic activity. Preferably it cleaves the ester and peptide bonds adjacent to the C-termini of hydrophobic, aliphatic, or aromatic amino acids. CUSABIO’s recombinant proteinase K is highly pure determined by SDS-PAGE and reaches up […]