Extramedullary plasmacytoma (EMP) represents a definite but uncommon entity among the many plasma cell neoplasms. Given its rarity, no therapeutic consensus has been met. We report the case of a 57-year-old man with a one-year historical past of nasal congestion and occasional dyspnoea. Imaging confirmed a hypermetabolic mass in the proper nasopharynx extending backward in the direction of the adjoining oropharynx, infiltrating the epiglottis. As incisional biopsy confirmed histologic and immunophenotypic options in step with plasma cell neoplasm, whereas the potential of a marginal zone lymphoma with plasmacytic differentiation was included within the differential analysis.
A ultimate analysis of EMP was reached by utilizing circulation cytometry (FC) of a cell suspension from the neoplastic tissue. The affected person obtained native radiotherapy (RT) which resulted to finish remission. In conclusion, circulation cytometry would possibly function an auxiliary methodology in circumstances the place immunohistochemistry can’t differentiate between a plasma cell dyscrasia and a B-non-Hodgkin lymphoma. In circumstances of a longtime analysis of solitary nasopharyngeal EMP RT represents a wonderful therapy modality providing extended disease-free survival.
Though circulation cytometry and cell sorting are broadly utilized by immunologists each for fundamental and translation analysis, many facets of those methods needs to be optimized to acquire reproducible and significant knowledge. On this chapter we offer some protocols and recommendations on instrument setting, multicolor panel design and T-cell immunophenotyping and proliferation assay.
Multiparametric circulation cytometry is a extremely delicate methodology to determine and quantify malignant PCs. And the ratio of malignant PCs detected by MFC confirmed strongly correlation with the severity of the pathology of MM. Malignant PCs in BM detected by circulation cytometry might be thought to be a predictor for the danger stratification system of MM. Thus, it needs to be thought-about making use of within the routine analysis of MM at analysis and after remedy.
Strategies for Characterization of Senescent Circulating and Tumor-Infiltrating T-Cells: An Overview from Multicolor Movement Cytometry to Single-Cell RNA Sequencing
Immunosenescence is the final time period used to explain the aging-associated decline of immunological operate that explains the upper susceptibility to infectious illnesses and most cancers, elevated autoimmunity, or the decreased effectiveness of vaccinations. Senescence of CD8+ T-cells has been described in all these circumstances.An important classical markers of T senescent cells are the cell cycle inhibitors p16ink4a, p21, and p53, along with positivity for SA-βgal expression and the acquirement of a peculiar IFNγ -based secretory phenotype generally outlined SASP (Senescence Related Secretory Phenotype).
Different floor markers are the CD28 and CD27 loss along with acquire of expression of CD45RA, CD57, TIGIT, and/or KLRG1. Nonetheless, this characterization couldn’t be ample to tell apart from actually senescent cells and exhausted T-cells. Moreover, extra complexity is added by the large heterogeneity of T-cells subset in aged people or within the tumor microenvironment. A mixed evaluation by multicolor circulation cytometry for floor and intracellular markers built-in with gene-expression arrays and single-cell RNA sequencing is required to develop efficient interventions for therapeutic modulation of particular T-cell subsets.
The RNASeq presents the good chance to disclose at single-cell decision the precise molecular hallmarks of senescent CD8+ T-cells with out the constraints of bulk evaluation. Moreover, the great integration of multidimensional approaches (genomics, epigenomics, proteomics, metabolomics) will enhance our world understanding of how immunosenescence of T-cells is interlinked to human ageing.
In Vivo Movement Cytometry
In vivo circulation cytometry (IVFC) was first designed to detect circulating cells in a mouse ear. It permits real-time monitoring of cells in peripheral blood without having to attract blood. The IVFC discipline has made nice progress over the past decade with the event of fluorescence, photoacoustic, and multiphoton microscopy. Furthermore, the appliance of IVFC is not restricted to circulating cells. IVFC based mostly on fluorescence and photoacoustic are most generally utilized in biomedical analysis. Strategies based mostly on fluorescence are sometimes used for object monitoring in superficial vessels, whereas strategies based mostly on photoacoustics have a bonus of label-free monitoring in deep vessels. On this chapter, we introduce technical factors and key purposes of IVFC.
We concentrate on the ideas, labeling methods, sensitivity, and biomedical purposes of the know-how. As well as, we summarize this chapter and focus on essential analysis instructions of IVFC sooner or later. This can be a cross-sectional, case-control examine together with 60 sufferers with systemic lupus erythematosus and 20 sex- and age-matched wholesome controls. A 14-color immunophenotyping panel was utilized to detect proportions of circulating immune mononuclear cells, and comparisons between sufferers and wholesome controls, and subgroups of sufferers, had been carried out. Correlations between mobile proportions and different parameters had been investigated.
On-chip imaging circulation cytometry has been broadly utilized in most cancers biology, immunology, microbiology, and drug discovery. Pure optical imaging mixed with circulation cytometry to derive chemical, structural, and morphological options of cells supplies systematic insights into organic processes. Nonetheless, as a result of excessive focus and powerful optical attenuation of purple blood cells, preprocessing is important for optical circulation cytometry whereas coping with entire blood.
Anti-IL3RA antibody (Alexa-fluor 647) |
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STJ170011 | St John's Laboratory | 100 µg | EUR 393 |
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment |
Anti-CD207 antibody (Alexa-fluor 488) |
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STJ170014 | St John's Laboratory | 100 µg | EUR 393 |
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307) |
Anti-CD207 antibody (Alexa-fluor 546) |
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STJ170015 | St John's Laboratory | 100 µg | EUR 393 |
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307) |
Anti-CD207 antibody (Alexa-fluor 647) |
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STJ170016 | St John's Laboratory | 100 µg | EUR 393 |
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307) |
Anti-IL7R antibody (Alexa-fluor 488) |
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STJ170020 | St John's Laboratory | 100 µg | EUR 393 |
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54) |
Anti-IL7R antibody (Alexa-fluor 546) |
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STJ170021 | St John's Laboratory | 100 µg | EUR 393 |
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54) |
Anti-IL7R antibody (Alexa-fluor 647) |
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STJ170022 | St John's Laboratory | 100 µg | EUR 393 |
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54) |
SAM FCM (Alexa Fluor 647) |
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abx098902-100tests | Abbexa | 100 tests | EUR 1233 |
SAM FCM (Alexa Fluor 488) |
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abx098904-60tests | Abbexa | 60 tests | EUR 1358 |
Anti-RPSA Alexa Fluor® 488 |
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A4-829-C100 | ExBio | 0.1 mg | EUR 310 |
Anti-Hu CD16 Alexa Fluor® 488 |
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A4-646-T100 | ExBio | 100 tests | EUR 269 |
Goat anti Mouse IgG1 (Alexa Fluor 488) |
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43R-1649 | Fitzgerald | 500 ug | EUR 570 |
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488) |
Alpha Fluor™ 532 acid [equivalent to Alexa Fluor™ 532 acid] |
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1795 | AAT Bioquest | 10 mg | EUR 393 |
Mouse IgG1-Alexa 555 conjugate (isotype control) |
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20102-101-A555 | Alpha Diagnostics | 50 Tests | EUR 263 |
AF350-streptavidin conjugate [Streptavidin, Alexa Fluor™ 350 Conjugate] |
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16890 | AAT Bioquest | 1 mg | EUR 176 |
AF488-streptavidin conjugate [Streptavidin, Alexa Fluor™ 488 Conjugate] |
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16891 | AAT Bioquest | 1 mg | EUR 176 |
AF594-streptavidin conjugate [Streptavidin, Alexa Fluor™ 594 Conjugate] |
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16892 | AAT Bioquest | 1 mg | EUR 176 |
AF350 Phalloidin [equivalent to Alexa Fluor® 350 phalloidin] |
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23150 | AAT Bioquest | 300 Tests | EUR 306 |
AF488 Phalloidin [equivalent to Alexa Fluor® 488 phalloidin] |
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23153 | AAT Bioquest | 300 Tests | EUR 306 |
AF594 Phalloidin [equivalent to Alexa Fluor® 594 phalloidin] |
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23158 | AAT Bioquest | 300 Tests | EUR 306 |
Anti-Hu CD72 Alexa Fluor® 488 |
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A4-310-T100 | ExBio | 100 tests | EUR 269 |
Anti-Bov CD9 Alexa Fluor® 488 |
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A4-354-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD30 Alexa Fluor® 700 |
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A7-455-T100 | ExBio | 100 tests | EUR 269 |
Anti-Hu CD94 Alexa Fluor® 700 |
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A7-727-T100 | ExBio | 100 tests | EUR 269 |
Anti-Hu CD56 Alexa Fluor® 700 |
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A7-789-T100 | ExBio | 100 tests | EUR 269 |
Donkey anti Goat IgG (H + L) (Alexa Fluor 594) |
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43R-ID005AF | Fitzgerald | 500 ug | EUR 338 |
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 594) |
Donkey anti Rat IgG (H + L) (Alexa Fluor 594) |
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43R-ID022AF | Fitzgerald | 500 ug | EUR 364 |
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594) |
Donkey anti Goat IgG (H + L) (Alexa Fluor 647) |
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43R-ID028AF | Fitzgerald | 500 ug | EUR 430 |
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647) |
Donkey anti Rat IgG (H + L) (Alexa Fluor 594) |
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43R-ID047AF | Fitzgerald | 500 ug | EUR 462 |
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594) |
Donkey anti Chicken IgY (H + L) (Alexa Fluor 594) |
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43R-ID056AF | Fitzgerald | 500 ug | EUR 343 |
Description: Donkey anti Chicken IgY secondary antibody (H + L) (Alexa Fluor 594) |
Donkey anti Chicken IgY (H + L) (Alexa Fluor 647) |
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43R-ID060AF | Fitzgerald | 300 ug | EUR 425 |
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647) |
Rabbit anti Chicken IgY (H + L) (Alexa Fluor 594) |
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43R-IR016AF | Fitzgerald | 1 mg | EUR 281 |
Description: Rabbit anti Chicken IgY (H + L) secondary antibody (Alexa Fluor 594) |
SDCCAG8 Antibody |
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1-CSB-PA006722 | Cusabio |
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Description: A polyclonal antibody against SDCCAG8. Recognizes SDCCAG8 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/20000 |
SDCCAG8 Antibody |
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1-CSB-PA020899GA01HU | Cusabio |
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Description: A polyclonal antibody against SDCCAG8. Recognizes SDCCAG8 from Human, Mouse, Rat, Zebrafish. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF |
SDCCAG8 Antibody |
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43294-100ul | SAB | 100ul | EUR 252 |
SDCCAG8 Antibody |
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ABD8846 | Lifescience Market | 100 ug | EUR 438 |
SDCCAG8 Antibody |
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DF8846 | Affbiotech | 200ul | EUR 304 |
Description: SDCCAG8 Antibody detects endogenous levels of total SDCCAG8. |
SDCCAG8 antibody |
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70R-20131 | Fitzgerald | 50 ul | EUR 435 |
Description: Rabbit polyclonal SDCCAG8 antibody |
SDCCAG8 antibody |
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70R-4002 | Fitzgerald | 50 ug | EUR 467 |
Description: Rabbit polyclonal SDCCAG8 antibody raised against the N terminal of SDCCAG8 |
SDCCAG8 antibody |
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70R-4128 | Fitzgerald | 50 ug | EUR 467 |
Description: Rabbit polyclonal SDCCAG8 antibody raised against the middle region of SDCCAG8 |
Goat Anti-Mouse IgG(H+L) Alexa Fluor 594–conjugated |
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S0005 | Affbiotech | 200ul | EUR 376 |
Goat Anti-Rabbit IgG(H+L) Alexa Fluor 594–conjugated |
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S0006 | Affbiotech | 200ul | EUR 376 |
Goat Anti-Rabbit IgG(H+L) Alexa Fluor 647–conjugated |
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S0013 | Affbiotech | 200ul | EUR 304 |
Goat Anti-Mouse IgG(H+L) Alexa Fluor 647–conjugated |
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S0014 | Affbiotech | 200ul | EUR 304 |
Goat Anti-Mouse IgG(H+L) Alexa Fluor 488–conjugated |
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S0017 | Affbiotech | 200ul | EUR 304 |
Goat Anti-Rabbit IgG(H+L) Alexa Fluor 488–conjugated |
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S0018 | Affbiotech | 200ul | EUR 304 |
Anti-LAMP3 (human) Monoclonal Antibody (104G4) (Alexa Fluor® 488) |
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M09406 | BosterBio | 100ug | EUR 565 |
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human. |
Anti-SDCCAG8 antibody |
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STJ72779 | St John's Laboratory | 100 µg | EUR 359 |
SDCCAG8 Conjugated Antibody |
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C43294 | SAB | 100ul | EUR 397 |
anti- SDCCAG8 antibody |
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FNab07666 | FN Test | 100µg | EUR 505.25 |
Description: Antibody raised against SDCCAG8 |
Anti-SDCCAG8 antibody |
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PAab07666 | Lifescience Market | 100 ug | EUR 355 |
Donkey Anti-Goat IgG (H+L), Alexa Fluor® 594 Conjugated |
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Ab8011-001 | GenDepot | 1mg | EUR 334 |
Donkey Anti-Rabbit IgG (H+L), Alexa Fluor® 488 Conjugated |
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Ab8032-001 | GenDepot | 0.5mg | EUR 435 |
Anti-Hu CD3 zeta (pY153) Alexa Fluor® 488 |
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A4-686-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD3 zeta (pY72) Alexa Fluor® 488 |
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A4-712-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD3 zeta (pY142) Alexa Fluor® 488 |
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A4-730-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD3 zeta (pY111) Alexa Fluor® 488 |
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A4-737-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647 |
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A6-686-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD3 zeta (pY72) Alexa Fluor® 647 |
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A6-712-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647 |
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A6-730-C100 | ExBio | 0.1 mg | EUR 269 |
Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647 |
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A6-737-C100 | ExBio | 0.1 mg | EUR 269 |
Donkey anti Goat IgG (H + L) (Fab 2) (Alexa Fluor 594) |
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43R-ID012AF | Fitzgerald | 300 ug | EUR 410 |
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594) |
Anti-Langerin (human) Monoclonal Antibody (DCGM4/122D5) (Alexa Fluor® 488) |
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M02316 | BosterBio | 100ug | EUR 580 |
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human. |
SDCCAG8 siRNA |
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20-abx932704 | Abbexa |
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SDCCAG8 siRNA |
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20-abx932705 | Abbexa |
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anti-SDCCAG8 |
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YF-PA17224 | Abfrontier | 50 ul | EUR 363 |
Description: Mouse polyclonal to SDCCAG8 |
anti-SDCCAG8 |
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YF-PA17225 | Abfrontier | 50 ug | EUR 363 |
Description: Mouse polyclonal to SDCCAG8 |
SDCCAG8 Peptide |
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43-022P | ProSci | 0.1 mg | EUR 338 |
Description: SDCCAG8 Peptide |
SDCCAG8 Peptide |
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43-023P | ProSci | 0.1 mg | EUR 338 |
Description: SDCCAG8 Peptide |
Polyclonal SDCCAG8 Antibody (Internal) |
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APG01216G | Leading Biology | 0.05mg | EUR 484 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human SDCCAG8 (Internal). This antibody is tested and proven to work in the following applications: |
SDCCAG8 cloning plasmid |
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CSB-CL020899HU-10ug | Cusabio | 10ug | EUR 413 |
Description: A cloning plasmid for the SDCCAG8 gene. |
SDCCAG8 Blocking Peptide |
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20-abx161437 | Abbexa |
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SDCCAG8 Blocking Peptide |
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DF8846-BP | Affbiotech | 1mg | EUR 195 |
SDCCAG8 Blocking Peptide |
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33R-3716 | Fitzgerald | 100 ug | EUR 180 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SDCCAG8 antibody, catalog no. 70R-4002 |
SDCCAG8 Blocking Peptide |
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33R-4109 | Fitzgerald | 100 ug | EUR 180 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SDCCAG8 antibody, catalog no. 70R-4128 |
Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG) |
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50336 | Alpha Diagnostics | 0.5 ml | EUR 225 |
Rabbit Anti-Rat IgG (H+L)-Alexa 594 Fluor conjugate (adsorbed with human IgG) |
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50337 | Alpha Diagnostics | 0.5 ml | EUR 225 |
Polyclonal SDCCAG8 Antibody (internal region) |
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APG00810G | Leading Biology | 0.1mg | EUR 484 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human SDCCAG8 (internal region). This antibody is tested and proven to work in the following applications: |
Polyclonal SDCCAG8 Antibody (aa469-483) |
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APG01240G | Leading Biology | 0.05mg | EUR 484 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human SDCCAG8 (aa469-483). This antibody is tested and proven to work in the following applications: |
Anti-SDCCAG8 (aa469-483) antibody |
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STJ72780 | St John's Laboratory | 100 µg | EUR 359 |
Mouse SDCCAG8 shRNA Plasmid |
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20-abx978693 | Abbexa |
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Human SDCCAG8 shRNA Plasmid |
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20-abx957365 | Abbexa |
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SDCCAG8 ELISA KIT|Human |
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EF002773 | Lifescience Market | 96 Tests | EUR 689 |
Human SDCCAG8 ELISA KIT |
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ELI-29645h | Lifescience Market | 96 Tests | EUR 824 |
Mouse Sdccag8 ELISA KIT |
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ELI-13424m | Lifescience Market | 96 Tests | EUR 865 |
pCMV-SPORT6-SDCCAG8 Plasmid |
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PVT16613 | Lifescience Market | 2 ug | EUR 325 |
SDCCAG8 Recombinant Protein (Mouse) |
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RP170432 | ABM | 100 ug | Ask for price |
SDCCAG8 Recombinant Protein (Human) |
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RP096258 | ABM | 100 ug | Ask for price |
SDCCAG8 Recombinant Protein (Rat) |
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RP227798 | ABM | 100 ug | Ask for price |
AG 555 |
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HY-15336 | MedChemExpress | 10mM/1mL | EUR 126 |
AG 555 |
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B6377-10 | ApexBio | 10 mg | EUR 144 |
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation. |
AG 555 |
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B6377-25 | ApexBio | 25 mg | EUR 276 |
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation. |
On this examine, we develop an on-chip photoacoustic imaging circulation cytometry (PAIFC), which mixes multicolor high-speed photoacoustic microscopy and microfluidics for cell imaging. The machine employs a micro-optical scanner to realize a miniaturized outer dimension of 30 × 17 × 24 mm3 and ultrafast cross-sectional imaging at a body price of 1758 Hz and supplies lateral and axial resolutions of two.2 and 33 μm, respectively.