Highly sensitive detection of antibody nonspecific interactions using flow cytometry

The quickly evolving nature of antibody drug improvement has resulted in applied sciences that generate huge numbers (a whole bunch to hundreds) of lead antibody candidates throughout early discovery. These candidates have to be quickly pared all the way down to establish probably the most drug-like candidates for in-depth evaluation of their security and efficacy, which may solely be carried out on a restricted variety of antibodies attributable to time and useful resource necessities. One key biophysical property of profitable antibody therapeutics is excessive specificity, outlined as low ranges of nonspecific binding or polyspecificity.

Though there was some progress in creating assays for detecting antibody polyspecificity, most of those assays are restricted by poor sensitivity or assay codecs that require proprietary antibody floor show strategies, and a few of these assays use advanced and poorly outlined polyspecificity reagents. Right here we report the PolySpecificity Particle (PSP) assay, a delicate circulation cytometry assay for evaluating antibody nonspecific interactions that overcomes earlier limitations and can be utilized for evaluating various sorts of IgGs, multispecific antibodies and Fc-fusion proteins. Our strategy makes use of micron-sized magnetic beads coated with Protein A to seize antibodies at extraordinarily dilute concentrations (<0.02 mg/mL).

Move cytometry evaluation of polyspecificity reagent binding to those conjugates ends in delicate detection of variations in nonspecific interactions for clinical-stage antibodies. Our PSP assay strongly discriminates between antibodies with totally different ranges of polyspecificity utilizing beforehand reported polyspecificity reagents which are both well-defined proteins or extremely advanced protein mixtures. Furthermore, we additionally discover {that a} distinctive reagent, particularly ovalbumin, ends in the very best assay sensitivity and specificity. Importantly, our assay is far more delicate than customary assays equivalent to ELISAs. We anticipate that our easy, delicate, and high-throughput PSP assay will speed up the event of protected and efficient antibody therapeutics.

Toxicity of Carbon Nanomaterials-In the direction of Dependable Viability Evaluation by way of New Method in Move Cytometry

The scope of software of carbon nanomaterials in biomedical, environmental and industrial fields is lately considerably growing. Since in vitro toxicity testing is the primary important step for any business utilization, it’s essential to have a dependable methodology to investigate the possibly dangerous results of carbon nanomaterials. Regardless that researchers already reported the interference of carbon nanomaterials with widespread toxicity assays, there’s nonetheless, sadly, a lot of research that neglect this reality. On this research, we investigated interference of 4 bio-promising carbon nanomaterials (graphene acid (GA), cyanographene (GCN), graphitic carbon nitride (g-C3N4) and carbon dots (QCDs)) in generally used LIVE/DEAD assay.

When a regular process was utilized, supplies prompted varied sorts of interference. Whereas positively charged g-C3N4 and QCDs induced false outcomes by means of the creation of free agglomerates and intrinsic fluorescence properties, negatively charged GA and GCN led to false indicators as a result of advanced quenching impact of the fluorescent dye of a LIVE/DEAD package. Thus, we developed a brand new strategy utilizing a particular gating technique primarily based on extra controls that efficiently overcame all sorts of interference and result in dependable ends in LIVE/DEAD assay.

We advise that the newly developed process ought to be a compulsory device for all in vitro circulation cytometry assays of any class of carbon nanomaterials. Imaging circulation cytometry permits for the quantitative evaluation of fluorescent indicators on the subcellular degree. Right here, we describe using a biosensor cell line, particularly, U2OS osteosarcoma cells outfitted with a fusion protein comprising monomeric pink fluorescent protein (mRFP), inexperienced fluorescent protein (GFP) and microtubule-associated proteins 1A/1B gentle chain 3B (greatest often called LC3), for the evaluation of autophagic flux by imaging circulation cytometry.

Highly sensitive detection of antibody nonspecific interactions using flow cytometry

We element all evaluation instruments required to tell apart autophagosomes (that emit each a pink and a inexperienced fluorescence) and autolysosomes (that emit a pink fluorescence, but lose the inexperienced fluorescent sign) and to quantitate autophagic flux in a handy style. Our information, nevertheless, present that information of the kinetics of the interplay permits to reconcile the info obtained by circulation cytometry and LigandTracer and show the complementarity of those two strategies.

Okay D willpower from time-resolved experiments on stay cells with LigandTracer and reconciliation with end-point circulation cytometry measurements

Design of next-generation therapeutics comes with new challenges and emulates expertise and strategies to satisfy them. Characterizing the binding of both pure ligands or therapeutic proteins to cell-surface receptors, for which related recombinant variations could not exist, represents certainly one of these challenges. Right here we report the characterization of the interplay of 5 totally different antibody therapeutics (Trastuzumab, Rituximab, Panitumumab, Pertuzumab, and Cetuximab) with their cognate goal receptors utilizing LigandTracer.

MCCC2 Antibody

DF12655-100ul 100ul
EUR 280

MCCC2 Antibody

DF12655-200ul 200ul
EUR 350

MCCC2 antibody

E39-05048 100ug/100ul
EUR 225
Description: Available in various conjugation types.

MCCC2 Antibody

E97990 100ul
EUR 255
Description: Available in various conjugation types.

MCCC2 Antibody

E306903 100ug/200ul
EUR 275
Description: Available in various conjugation types.

MCCC2 antibody

70R-18436 50 ul
EUR 289
Description: Rabbit polyclonal MCCC2 antibody

MCCC2 Antibody

MBS7045492-005mL 0.05mL
EUR 190

MCCC2 Antibody

MBS7045492-01mL 0.1mL
EUR 270

MCCC2 Antibody

MBS7045492-5x01mL 5x0.1mL
EUR 1205

Mccc2 Antibody

MBS9014731-INQUIRE INQUIRE Ask for price

MCCC2 Antibody

MBS8500390-01mg 0.1mg
EUR 345

MCCC2 Antibody

MBS8500390-01mLAF405L 0.1mL(AF405L)
EUR 565

MCCC2 Antibody

MBS8500390-01mLAF405S 0.1mL(AF405S)
EUR 565

MCCC2 Antibody

MBS8500390-01mLAF610 0.1mL(AF610)
EUR 565

MCCC2 Antibody

MBS8500390-01mLAF635 0.1mL(AF635)
EUR 565

MCCC2 Antibody

MBS9611407-01mL 0.1mL
EUR 260

MCCC2 Antibody

MBS9611407-02mL 0.2mL
EUR 305

MCCC2 Antibody

MBS9611407-5x02mL 5x0.2mL
EUR 1220

MCCC2 Antibody (Center)

MBS9231845-01mL 0.1mL
EUR 435

MCCC2 Antibody (Center)

MBS9231845-5x01mL 5x0.1mL
EUR 1625

MCCC2 Antibody (Center)

MBS9214337-008mL 0.08mL
EUR 210

MCCC2 Antibody (Center)

MBS9214337-04mL 0.4mL
EUR 430

MCCC2 Antibody (Center)

MBS9214337-5x04mL 5x0.4mL
EUR 1910

MCCC2 Antibody (C-term)

MBS9211665-008mL 0.08mL
EUR 210

MCCC2 Antibody (C-term)

MBS9211665-04mL 0.4mL
EUR 430

MCCC2 Antibody (C-term)

MBS9211665-5x04mL 5x0.4mL
EUR 1910

MCCC2 Polyclonal Antibody

28858 100ul
EUR 439

MCCC2 Polyclonal Antibody

28858-100ul 100ul
EUR 302.4

MCCC2 Polyclonal Antibody

28858-50ul 50ul
EUR 224.4

MCCC2 Polyclonal Antibody

31405 100ul
EUR 439

MCCC2 Polyclonal Antibody

31405-100ul 100ul
EUR 302.4

MCCC2 Polyclonal Antibody

31405-50ul 50ul
EUR 224.4

MCCC2 Polyclonal Antibody

E915181 100ul
EUR 225
Description: Available in various conjugation types.

MCCC2 Polyclonal Antibody

E-AB-66453-120uL 120uL
EUR 320
Description: Unconjugated

MCCC2 Polyclonal Antibody

E-AB-66453-200uL 200uL
EUR 530
Description: Unconjugated

MCCC2 Polyclonal Antibody

E-AB-66453-60uL 60uL
EUR 200
Description: Unconjugated

MCCC2 Polyclonal Antibody

E-AB-66453-each each Ask for price
Description: Unconjugated

MCCC2 Polyclonal Antibody

MBS9135167-002mL 0.02mL
EUR 200

MCCC2 Polyclonal Antibody

MBS9135167-005mL 0.05mL
EUR 255

MCCC2 Polyclonal Antibody

MBS9135167-01mL 0.1mL
EUR 345

MCCC2 Polyclonal Antibody

MBS9135167-02mL 0.2mL
EUR 545

MCCC2 Polyclonal Antibody

MBS9135167-5x02mL 5x0.2mL
EUR 2265

MCCC2 Polyclonal Antibody

MBS9128127-002mL 0.02mL
EUR 200

MCCC2 Polyclonal Antibody

MBS9128127-005mL 0.05mL
EUR 255

MCCC2 Polyclonal Antibody

MBS9128127-01mL 0.1mL
EUR 345

MCCC2 Polyclonal Antibody

MBS9128127-02mL 0.2mL
EUR 545

MCCC2 Polyclonal Antibody

MBS9128127-5x02mL 5x0.2mL
EUR 2265

MCCC2 Polyclonal Antibody

MBS8569866-01mL 0.1mL
EUR 305

MCCC2 Polyclonal Antibody

MBS8569866-01mLAF405L 0.1mL(AF405L)
EUR 565

MCCC2 Polyclonal Antibody

MBS8569866-01mLAF405S 0.1mL(AF405S)
EUR 565

MCCC2 Polyclonal Antibody

MBS8569866-01mLAF610 0.1mL(AF610)
EUR 565

MCCC2 Polyclonal Antibody

MBS8569866-01mLAF635 0.1mL(AF635)
EUR 565

MCCC2 Polyclonal Antibody

MBS2565285-006mL 0.06mL
EUR 190

MCCC2 Polyclonal Antibody

MBS2565285-012mL 0.12mL
EUR 265

MCCC2 Polyclonal Antibody

MBS2565285-02mL 0.2mL
EUR 415

MCCC2 Polyclonal Antibody

MBS2565285-5x02mL 5x0.2mL
EUR 1835

MCCC2 Polyclonal Antibody

MBS2541634-006mL 0.06mL
EUR 190

MCCC2 Polyclonal Antibody

MBS2541634-012mL 0.12mL
EUR 265

MCCC2 Polyclonal Antibody

MBS2541634-02mL 0.2mL
EUR 415

MCCC2 Polyclonal Antibody

MBS2541634-5x02mL 5x0.2mL
EUR 1835

MCCC2 Polyclonal Antibody

MBS9434236-005mL 0.05mL
EUR 300

MCCC2 Polyclonal Antibody

MBS9434236-01mL 0.1mL
EUR 390

MCCC2 Polyclonal Antibody

MBS9434236-5x01mL 5x0.1mL
EUR 1610

MCCC2 Polyclonal Antibody

MBS9432452-005mL 0.05mL
EUR 300

MCCC2 Polyclonal Antibody

MBS9432452-01mL 0.1mL
EUR 390

MCCC2 Polyclonal Antibody

MBS9432452-5x01mL 5x0.1mL
EUR 1610

MCCC2 Polyclonal Antibody

RD84846A-120uL 120μL
EUR 360
Description: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

MCCC2 Polyclonal Antibody

RD84846A-200uL 200μL
EUR 630
Description: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

MCCC2 Polyclonal Antibody

RD84846A-60uL 60μL
EUR 204
Description: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

MCCC2 Polyclonal Antibody

RD266453A-120uL 120μL
EUR 360
Description: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

MCCC2 Polyclonal Antibody

RD266453A-200uL 200μL
EUR 630
Description: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

MCCC2 Polyclonal Antibody

RD266453A-60uL 60μL
EUR 204
Description: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

MCCC2 polyclonal antibody

BS71037 50ul
EUR 208
Description: Rabbit

MCCC2 polyclonal antibody

BS76164 50ul
EUR 208
Description: Rabbit

OACD00477-1ML - MCCC2 Antibody

OACD00477-1ML 1ml
EUR 739

OACD00478-1ML - MCCC2 Antibody

OACD00478-1ML 1ml
EUR 649

OAAN02555-50UL - MCCC2 Antibody

OAAN02555-50UL 50ul
EUR 149

OACA08635-50UL - MCCC2 Antibody

OACA08635-50UL 50ul
EUR 189

Polyclonal MCCC2 Antibody (Center)

APR10893G 0.1ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MCCC2 (Center). This antibody is tested and proven to work in the following applications:

OACD00477-100UL - MCCC2 Antibody

OACD00477-100UL 100ul
EUR 209

OACD00478-100UL - MCCC2 Antibody

OACD00478-100UL 100ul
EUR 199

OAAN02555-100UL - MCCC2 Antibody

OAAN02555-100UL 100ul
EUR 249

OAAN02555-200UL - MCCC2 Antibody

OAAN02555-200UL 200ul
EUR 389

OAAL00786-100UG - MCCC2 Antibody

OAAL00786-100UG 100ug
EUR 349

OAGA01973-100UL - MCCC2 Antibody

OAGA01973-100UL 100ul
EUR 369

OAGA05503-100UL - MCCC2 Antibody

OAGA05503-100UL 100ul
EUR 369

OACA08635-100UL - MCCC2 Antibody

OACA08635-100UL 100ul
EUR 230

[One Step] MCCC2 Antibody Kit

RK05665 50 ul
EUR 288

[One Step] MCCC2 Antibody Kit

MBS9145415-002mL 0.02mL
EUR 200

[One Step] MCCC2 Antibody Kit

MBS9145415-005mL 0.05mL
EUR 255

[One Step] MCCC2 Antibody Kit

MBS9145415-01mL 0.1mL
EUR 345

[One Step] MCCC2 Antibody Kit

MBS9145415-02mL 0.2mL
EUR 545

[One Step] MCCC2 Antibody Kit

MBS9145415-5x02mL 5x0.2mL
EUR 2265

MCCC2 Antibody - C-terminal region

MBS3208154-01mL 0.1mL
EUR 455

MCCC2 Antibody - C-terminal region

MBS3208154-5x01mL 5x0.1mL
EUR 1995

MCCC2 Antibody - N-terminal region

MBS3208155-01mL 0.1mL
EUR 455

MCCC2 Antibody - N-terminal region

MBS3208155-5x01mL 5x0.1mL
EUR 1995

MCCC2 Antibody - C-terminal region

MBS3222074-01mL 0.1mL
EUR 455

MCCC2 Antibody - C-terminal region

MBS3222074-5x01mL 5x0.1mL
EUR 1995

MCCC2 Antibody (Center) Blocking Peptide

MBS9226431-INQUIRE INQUIRE Ask for price

MCCC2 Polyclonal Conjugated Antibody

C28858 100ul
EUR 476.4

MCCC2 Polyclonal Conjugated Antibody

C31405 100ul
EUR 476.4

MCCC2 Polyclonal Conjugated Antibody

MBS9442578-01mLAF350 0.1mL(AF350)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9442578-01mLAF405 0.1mL(AF405)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9442578-01mLAF488 0.1mL(AF488)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9442578-01mLAF555 0.1mL(AF555)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9442578-01mLBiotin 0.1mL(Biotin)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9440456-01mLAF350 0.1mL(AF350)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9440456-01mLAF405 0.1mL(AF405)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9440456-01mLAF488 0.1mL(AF488)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9440456-01mLAF555 0.1mL(AF555)
EUR 480

MCCC2 Polyclonal Conjugated Antibody

MBS9440456-01mLBiotin 0.1mL(Biotin)
EUR 480

MCCC2 Antibody (C-term) Blocking Peptide

MBS9223909-INQUIRE INQUIRE Ask for price

MCCC2 (Center) rabbit polyclonal antibody

AP17553PU-N 400 µl Ask for price

OAAB04039-400UL - MCCC2 Antibody - middle region

OAAB04039-400UL 400ul
EUR 409

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

20-abx006595
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx030686-400ul 400 ul
EUR 627.6

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx030686-80l 80 µl
EUR 343.2

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx037012-100ug 100 ug
EUR 469.2

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx033068-400ul 400 ul
EUR 627.6

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx033068-80l 80 µl
EUR 343.2

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx235048-100ug 100 ug
EUR 610.8

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

20-abx322517
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx037012-1096tests 10 × 96 tests Ask for price

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx037012-596tests 5 × 96 tests Ask for price

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx037012-96tests 96 tests
EUR 337.5

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx033068-400l 400 µl
EUR 518.75

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx030686-400l 400 µl
EUR 518.75

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx235048-100g 100 µg
EUR 350

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx322517-100g 100 µg
EUR 350

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx322517-50g 50 µg
EUR 250

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx006595-100g 100 µg
EUR 275

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx006595-10g 10 µg
EUR 175

Methylcrotonoyl-CoA Carboxylase 2 (MCCC2) Antibody

abx006595-200g 200 µg
EUR 400

ARP46313_P050-25UL - MCCC2 Antibody - C-terminal region

ARP46313_P050-25UL 25ul
EUR 99

ARP46314_P050-25UL - MCCC2 Antibody - N-terminal region

ARP46314_P050-25UL 25ul
EUR 99

ARP82826_P050-25UL - MCCC2 Antibody - C-terminal region

ARP82826_P050-25UL 25ul
EUR 99

OAAB14516-400UL - MCCC2 Antibody - C-terminal region

OAAB14516-400UL 400ul
EUR 389

ARP46313_P050 - MCCC2 Antibody - C-terminal region (ARP46313_P050)

ARP46313_P050 100ul
EUR 389

ARP46314_P050 - MCCC2 Antibody - N-terminal region (ARP46314_P050)

ARP46314_P050 100ul
EUR 389

ARP82826_P050 - MCCC2 Antibody - C-terminal region (ARP82826_P050)

ARP82826_P050 100ul
EUR 389

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody

20-abx131298
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody

20-abx131299
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody

20-abx113712
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody

abx113712-100l 100 µl
EUR 612.5

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody

abx131298-05mg 0.5 mg
EUR 275

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody

abx131299-05mg 0.5 mg
EUR 287.5

MCCC2

E8ER1912-86 100ul
EUR 275
Description: Available in various conjugation types.

MCCC2

CSB-CL867199HU1 10 μg plasmid + 200μl Glycerol Ask for price

MCCC2

CSB-CL867199HU2 10 μg plasmid + 200μl Glycerol Ask for price

MCCC2

MBS8577974-01mL 0.1mL
EUR 345

MCCC2

MBS8577974-01mLAF405L 0.1mL(AF405L)
EUR 565

MCCC2

MBS8577974-01mLAF405S 0.1mL(AF405S)
EUR 565

MCCC2

MBS8577974-01mLAF610 0.1mL(AF610)
EUR 565

MCCC2

MBS8577974-01mLAF635 0.1mL(AF635)
EUR 565

MCCC2

MBS8536600-01mL 0.1mL
EUR 325

MCCC2

MBS8536600-01mLAF405L 0.1mL(AF405L)
EUR 565

MCCC2

MBS8536600-01mLAF405S 0.1mL(AF405S)
EUR 565

MCCC2

MBS8536600-01mLAF610 0.1mL(AF610)
EUR 565

MCCC2

MBS8536600-01mLAF635 0.1mL(AF635)
EUR 565

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody

CAU23159-100ul 100ul
EUR 241.9

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody

CAU23159-200ul 200ul
EUR 302.4

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody

CAU23160-100ul 100ul
EUR 258.2

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody

CAU23160-200ul 200ul
EUR 322.6

MCCC2 siRNA

20-abx923707
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

MCCC2 siRNA

20-abx923708
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

MCCC2 siRNA

20-abx903187
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

PAD690Hu01 100ul
EUR 269

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033749-01mL 0.1mL
EUR 185

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033749-02mL 0.2mL
EUR 230

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033749-05mL 0.5mL
EUR 385

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033749-1mL 1mL
EUR 470

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033749-5mL 5mL
EUR 1295

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033847-01mL 0.1mL
EUR 175

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033847-02mL 0.2mL
EUR 220

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033847-05mL 0.5mL
EUR 365

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033847-1mL 1mL
EUR 445

Polyclonal Antibody to Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

MBS2033847-5mL 5mL
EUR 1220

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Human)

4-PAD690Hu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Mouse)

4-PAD690Mu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2)

Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102691-10x96Tests 10x96Tests
EUR 1480

Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102691-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1600

Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102691-5x96Tests 5x96Tests
EUR 935

Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102691-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1010

Mouse Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102692-10x96Tests 10x96Tests
EUR 1515

Mouse Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102692-10x96TestsMBS2090685AbPairsSupportPack110x96Tests 10x96Tests+MBS2090685(AbPairsSupportPack1,10x96Tests)
EUR 1640

Mouse Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102692-5x96Tests 5x96Tests
EUR 960

Mouse Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Antibody Pair Kit (with Standard)

MBS2102692-5x96TestsMBS2090685AbPairsSupportPack15x96Tests 5x96Tests+MBS2090685(AbPairsSupportPack1,5x96Tests)
EUR 1035

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Human), APC

4-PAD690Hu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2). This antibody is labeled with APC.

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Human), Cy3

4-PAD690Hu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2). This antibody is labeled with Cy3.

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Human), HRP

4-PAD690Hu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2). This antibody is labeled with HRP.

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Human), PE

4-PAD690Hu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2). This antibody is labeled with PE.

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Mouse), APC

4-PAD690Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2). This antibody is labeled with APC.

Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2) Polyclonal Antibody (Mouse), Cy3

4-PAD690Mu01-Cy3
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Methylcrotonoyl Coenzyme A Carboxylase 2 (MCCC2). This antibody is labeled with Cy3.

The tactic provides the benefit of being carried out on stay cells, assuaging the necessity for a recombinant supply of the receptor. Moreover, time-resolved measurements, along with permitting the willpower of the affinity of the studied drug to its goal, give entry to the binding kinetics thereby offering a full characterization of the system. On this research, we additionally in contrast time-resolved LigandTracer information with end-point OkayD willpower from circulation cytometry experiments and hypothesize that discrepancies between these two approaches, once they exist, typically come from circulation cytometry titration curves being acquired previous to full equilibration of the system.

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